A 48 year old male was referred for investigation of anemia.Results show:
Hemoglobin of 7.2 g/dL, White blood cell count of 3 x 10^9/l, platelet count of 60x 10^9/l.
On physical exam, his spleen was enlarged.
Peripheral blood showed teardrops and a leukoerythroblastic smear. Bone marrow biopsy showed increased numbers of megakaryocytes and grade III fibrosis.
What is the diagnosis?
a)-folate deficiency anaemia
b)-coomb’spositive haemolytic anaemia
c)-multiple myeloma
d)-myelofibrosis
e)-chronic myeloid leukemia
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