Question-239

A man has been on quitapine for 2 years. His serum testosterone is marginally lowered and prolactin 1500 iu. What is the most likely reason?


1-primary testicular failure

2-liver pathology

3-antipsychotic drug

Quitapine advers Adverse Effects
>10%
Dizziness

Dry mouth

Headache

Somnolence

1-10%
Abdominal pain

Constipation

Dyspepsia

Vomiting

Increased appetite

Weight gain

Agitation

Asthenia

Tremor

Back pain

Postural hypotension

Tachycardia

Fever

Pharyngitis

Rhinitis

Rash

Visual disturbances

Arthralgia

Frequency Not Defined
Hypercholesterolemia

Hypertriglyceridemia

Eye lens changes (rare)

Hyperglycemia

Hypothyroidism

Elevated liver function test results

Potential for new-onset diabetes

Postmarketing Reports
Anaphylactic reaction, Stevens-Johnson syndrome, toxic epidermal necrolysis

Cardiomyopathy, myocarditis

Hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH)

Nocturnal enuresis

Pancreatitis

Retrograde amnesia

Rhabdomyolysis

http://reference.medscape.com/drug/seroquel-xr-quetiapine-342984#4
also primary testicular failure laboratory findings donot support ang changing towards prolactin.
The third answer is not clear because quitapine is already antipsychotic drug.Thus the best chice seems to me is second answer.